The primary choice boils down to a fundamental dichotomy: do you need area-of-effect splash damage, or massive single-target elimination?
If you bring a single-target tower to a match against a swarm-heavy bait deck, you will be utterly annihilated.
Melting the Behemoths
The Inferno Tower is the ultimate example, possessing a damage beam that ramps up exponentially the longer it stays locked on a single target.
However, their massive, glaring weakness is their extreme vulnerability to cheap, multi-unit swarm cards.
It provides great value against fast units like the Hog Rider.It costs a massive amount of elixir and decays over time.Don't let the tank connect.
Clearing the Horde
Conversely, splash damage buildings, such as the Bomb Tower, are designed to obliterate massive groups of low-hitpoint enemies instantly.
If a heavy tank locks onto a Bomb Tower, the building will barely scratch the tank's armor before crumbling into dust.
Meta EnvironmentRecommended TowerHeavy Beatdown MetaInferno Tower is absolutely mandatory to survive the sheer health pools of the enemy pushesLog Bait / Swarm MetaBomb Tower provides incredible value and cannot be overwhelmed by sheer numbers
The Hybrid Approach and Deck Synergy
If you already run three area-of-effect spells, you probably do not need a splash damage building; take a single-target killer instead.
Master the placements of both architectural styles, and you will construct an impenetrable fortress.
Here is more in regards to tower rush stop by our own site.